FAQ

  • What causes damage to the liver?
    Psychological stress, long-term or heavy drinking of alcohol, obesity, smoking, consumption of processed food, having a family history of liver problems, or being exposed to certain toxins can be the causes for liver damage.1-4  
  • What are the possible treatments for liver problems?
    Both antiviral and immune-suppressing medications may be used in the management of liver problems.5  Also, changes of lifestyle can help manage certain liver problems, such as abstaining from alcohol, doing exercise to lose weight, limiting intake of fats and calories, and taking more fiber.5,6  Liver supplements such as milk thistle, artichoke leaf, and dandelion root may help detox the liver.7
  • Do supplements help address liver problems?
    For example, milk thistle contains an active substance known as silymarin, which is made up of several natural plant chemicals .7 The clinical trial has proven that silymarin is effective in reducing liver enzyme levels alanine aminotransferase (ALT), aspartate aminotransferase (AST), and γ-glutamyl transferase (GGT) in 8 weeks.8
  • What are the functions and characteristics of Legalon®?
    Legalon® contains the active ingredient of dry extract from milk thistle fruits, with a rich content of silymarin, calculated as silibinin .9 Legalon® is a formulation that promotes anti-inflammation, anti-fibrosis, antioxidation, liver detoxification, and the regeneration of liver cells.10-13 
  • How and when to take Legalon®？
    For adults and children 12 years old or above, 1 capsule of Legalon® should be taken 3 times a day, while the maintenance dose is 1 capsule 2 times a day.9 The whole capsule should be taken with some liquid before meals .13

References：

  1. Joung JY, et al. Brain Behav. 2019;9(3):e01235.
  2. Mayo Clinic. Available at: https://shorturl.at/mDIVW. Accessed Sep 2023.
  3. Zhang S, et al. Int J Epidemiol. 2022;51(1):237-249.
  4. Marti-Aguado D, et al. J Hepatol. 2022;77(1):191-205.
  5. Seladi-Schulman J, Williams A. Healthline. Available at: https://rb.gy/opfnx. Accessed Sep 2023.
  6. Stefano JT, et al. Ther Adv Endocrinol Metab. 2023;14:20420188231160394.
  7. Watson S. Healthline. Available at: https://www.healthline.com/health/liver-supplement. Accessed Sep 2023.
  8. Albrecht M, Frerick H, Kuhn U, et al. Z Klin Med. 1992;47:87-92.
  9. Legalon 140 Capsules Package Insert: Version M-Nr.229719.
  10. Gillessen A, Schmidt HH-J. Adv Ther. 2020;37(4):1279–1301.
  11. Trappoliere M, et al. J Hepatol. 2009;50(6):1102-1111.
  12. Lieber CS, et al. J Clin Gastroenterol. 2003;37(4):336-339.
  13. Post-White J, et al. Integr Can Ther. 2007;6(2):104-109.
PM-LEG-23-092202 Dec 2023